|本期目录/Table of Contents|

[1]林晓光.花生肽对小鼠运动能力及心肌抗氧化能力影响的研究[J].山东体育科技,2013,05:0.
 LIN Xiao-guang.Effects of peanut peptide on sport activity and myocardial antioxidant capacity of mice[J].,2013,05:0.
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花生肽对小鼠运动能力及心肌抗氧化能力影响的研究

《山东体育科技》[ISSN:1009-9840/CN:37-1011/G8]

期数:
2013年05期
页码:
0
栏目:
出版日期:
2013-10-25

文章信息/Info

Title:
Effects of peanut peptide on sport activity and myocardial antioxidant capacity of mice
作者:
林晓光
山东体育学院,山东 济南250102
Author(s):
LIN Xiao-guang
Shandong Sport University,Jinan 250102,Shandong,China
关键词:
花生肽小鼠心脏保护抗氧化
Keywords:
peanut peptide mouse heart protection antioxidant capacity
分类号:
G804.7
DOI:
-
文献标识码:
A
摘要:
目的:观察花生肽对小鼠运动能力和心肌抗氧化能力的影响。方法: 昆明种小鼠随机分为6 组,安静对照组、安静花生肽样品( 400 mg?kg-1 )组、运动对照组、运动花生肽样品高、中、低三个剂量组。运动各组进行连续4周的游泳训练,连续给药至第28天进行一次负重耐力实验。测定心肌丙二醛(MDA)含量和超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶( GSH-Px )活性,测定血清谷丙转氨酶(GPT)、谷草转氨酶 (GOT)、肌酸激酶(CK)活性。结果:花生肽处理组心肌MDA含量明显降低,心肌SOD、GSH-Px和CAT活性均高于相应的对照组。花生肽处理组小鼠运动能力显著增强。运动花生肽中剂量、运动花生肽高剂量组和运动对照组相比,血清中GPT、GOT和CK活性显著降低。结论:花生肽通过增强心肌抗氧化能力,减轻了剧烈运动对心脏造成的损伤,来发挥它的心脏保护作用。
Abstract:
Objective: To study the effects of peanut peptide on the sport activity and antioxidant capacity of mouse.Method:Sixty Kunming mice were randomly divided into six group, which were named normal group, peanut peptide group, exercised control group, exercised+peanut peptide in low content, exercised+peanut peptide in middle content, and exercised+peanut peptide in high content. The mouses of exercised groups were obtained swimming training for 4 weeks. At the last day of the experiment, the mice were experienced exhausted swimming bearing load. And then the content of MDA and the activity of SOD, CAT, GSH-Px in the heart tissue were detected with the correponding kit. The enzyme activity of GPT, GOT and CK in serum were assayed with kit, too. Results:The sports activity of mice treated with peanut peptide increased obviously compared with the control. The level of MDA decreased and the activity of antioxidant enzymes (SOD, CAT, GSHPx) in heart tissue elevated in peanut peptide groups. In the same time, the activity of cardiac marker enzyme in serum decreased obviously in exercised+peanut peptide groups of middle and high content. Conclusion:Peanut peptide might alleviate the cardiac damage induced by strenuous exercise and protect heart through enhancing myocardial antioxidant capacity.

参考文献/References

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更新日期/Last Update: 1900-01-01